The OncoFirm Platform
One reader. One strip design. A growing menu of antigen and antibody tests...
OncoFirm’s fluorescent lateral-flow platform was built first for cancer antigens such as CEA and PSA. The same strip format, handheld reader and software are designed to carry tests for sexually transmitted and respiratory infections, pregnancy and fertility, and heart, lung and blood conditions.
Design rendering of the OncoFirm handheld reader and test cassette. The reader measures how brightly the test line glows and reports a number.
Readout: quantitative, in unitsResult time target: ≤ 20 min
Conditions at a glance
What the platform is designed to test for
- Cancer
- Chlamydia
- Gonorrhea
- Syphilis
- Hepatitis B
- Hepatitis C
- HIV
- H. pylori
- Influenza
- COVID-19
- RSV
- Strep
- Legionella
- Mono
- Lyme disease
- Pregnancy and fertility
- Heart
- Lung
- Blood
- Inflammation
Sample to result
Three steps, the same for every test
01
Add a small sample
A drop of blood, a little urine, a swab or a stool sample, depending on the test.
02
Insert into the reader
The reader scans the full fluorescence profile and checks that the test ran correctly.
03
Get a number, logged
A quantitative result in minutes, saved to a traceable record without retyping.
How it works
Four parts that work the same for every test
Every strip carries a fluorescent reference line of known quantity, so each test checks its own calibration.
Stays the same for every new test
- Reader hardware and optics
- Strip format and reference line
- Signal analysis and quality checks
- Data format and reporting
Changes for each new test
- The antibody or antigen pair for the new target
- Its calibration settings
Fluorescent test strip
Antibodies labeled with bright fluorescent reporters capture the target in a small sample.
Built-in reference
A reference line of known fluorescence sits beside the test line, so lot, temperature and handling effects are corrected inside each test.
Handheld reader
The reader records the full fluorescence profile across the strip, not just a single spot, and flags tests that did not run correctly.
Software and data
AI-assisted analysis turns the profile into a numeric result, and cloud-enabled records keep results traceable across sites.
Infectious disease
Infectious disease tests the platform is designed to carry
Rapid infectious disease testing is where lateral flow proved itself. OncoFirm adds a quantitative, self-checking reader and connected data to that format.
Bloodborne and sexually transmitted infections
Blood, serum or swab samples. The STI tests make up the planned inSTIcheck™ line.
HBsAg
Hepatitis B
Surface antigen screening, with a numeric result that can support follow-up testing decisions.
Anti-HCV · HCV core antigen
Hepatitis C
Antibody screening, with a core-antigen format planned to help identify active infection.
HIV-1/2 antibody · p24 antigen
HIV
Rapid screening on the same reader used for the rest of the menu.
T. pallidum antibody
Syphilis
Rapid antibody screening from a small blood sample.
C. trachomatis antigen
Chlamydia
Swab-based screening for the most commonly reported bacterial STI in the United States.
N. gonorrhoeae antigen
Gonorrhea
Swab-based screening, designed to pair with the chlamydia test.
Respiratory and throat infections
Nasal, throat or urine samples, or a fingerstick for mono.
Influenza A/B antigen
Influenza
Flu A and B read by the instrument instead of by eye, with results logged automatically.
SARS-CoV-2 antigen
COVID-19
Designed to run alongside the flu test during respiratory season.
RSV antigen
RSV
Respiratory syncytial virus, a leading concern in young children and older adults.
Group A Streptococcus antigen
Strep throat
Throat-swab test to help guide antibiotic decisions at the point of care.
L. pneumophila urinary antigen
Legionella
Urine test for Legionnaires’ disease, a serious form of pneumonia.
EBV heterophile antibody
Mono
Infectious mononucleosis, caused by the Epstein-Barr virus.
Stomach and tick-borne infections
Stool or blood samples.
H. pylori stool antigen · antibody
H. pylori
A stomach infection linked to ulcers and to stomach cancer, which ties it to OncoFirm’s cancer focus.
Borrelia and other tick-borne pathogens
Lyme and tick-borne disease
A multi-pathogen panel read on one strip, aimed at earlier detection.
Beyond infection
Cancer, pregnancy and fertility, heart, lung and blood
CEA · PSA
Cancer
Quantitative cancer antigen testing, the program the platform was built for.
hCG · LH · FSH
Pregnancy and fertility
Pregnancy confirmation and hormone levels that help track ovulation and fertility.
NT-proBNP · troponin I
Heart
Heart failure monitoring and markers of heart muscle injury.
C-reactive protein
Inflammation
A general marker of inflammation and infection.
Procalcitonin · D-dimer
Lung and infection response
Help telling bacterial from viral infection, and a check for suspected blood clots.
Ferritin
Blood
Iron-deficiency anemia, a common condition that often goes untested.
Sample types vary by test: blood, serum or plasma, urine, swab or stool.
Experience
Experience with infectious disease rapid tests
Before founding OncoFirm, our CEO, Jonathan Adam Barash, worked at First Diagnostic Corporation on hepatitis B (HBsAg) and hepatitis C rapid tests that were recommended by the U.S. Army Medical Materiel Center–Europe (USAMMCE). OncoFirm brings that field experience to a new generation of quantitative, connected tests.
Development status. The OncoFirm platform and every test described on this page are in development. They have not been cleared or approved by the FDA and are not available for sale. Pictures are design renderings and illustrations, not photographs of finished products.
Partner with us
We are looking for research, clinical and distribution partners for the test menu. Tell us which test matters to your work.