Assays / Antigens and calibrators
Antigens and calibrators
Alpha-1-Microglobulin (A1M) — Native Antigen and Future Kidney Marker
Native alpha-1-microglobulin is used as calibrator, control and coating antigen, and is a candidate for a future quantitative urine assay for kidney tubular function.
At a glance
Material
Native human alpha-1-microglobulin (A1M)
Use
Calibrators, controls and coating antigen for ELISA or agglutination assays
Future assay
Quantitative urine A1M (pipeline)
Intended use
Research and manufacturing use only
Why it matters
Clinical context
Alpha-1-microglobulin is a small protein made mainly in the liver that helps protect tissues from oxidative damage. Healthy kidneys reabsorb it, so higher amounts in urine can signal kidney tubular dysfunction. That makes A1M both a useful reagent today and a candidate marker for a future OncoFirm urine test.
How it supports the platform
A foundation for quantitative assays
Reagent today
Characterized A1M serves as calibrator, control and coating antigen in in-vitro diagnostic development.
Kidney marker tomorrow
A quantitative urine A1M assay on the OncoFirm reader is a pipeline candidate.
Available to partners
Research and manufacturing partners can inquire about supply and specifications.
Where it's headed
Development roadmap
01
Characterization
Identity, purity and activity of the antigen are documented.
02
Use in OncoFirm assays
The material is used to build calibrators and controls during assay development and pilot lots.
03
Traceable value assignment
Calibrator values are linked to recognized reference materials as the related assays move toward validation.
Related assays
Intended use. For research and manufacturing use only. Not for use in diagnostic procedures. Assays described on this page are in development and have not been cleared or approved by the FDA.
Partner on this assay
We welcome research, clinical, manufacturing and distribution partners. Tell us how this assay fits your work.